Kane was involved in a collision with Fabian Delph on Tuesday night and left north London wearing a protective boot
Harry Kane’s season may well be over after picking up an ankle injury on Tuesday night against Manchester City.
The England captain attempted to make a robust challenge on Fabian Delph close to the sideline, but came off second best.
Kane left the Tottenham Hotspur Stadium wearing a protective boot and Mauricio Pochettino admitted the injury sustained to his left ankle could well be season-ending.
He told BT Sport: “We need to check tomorrow but it looks the same, a similar issue.
“Very sad, very disappointed, and it’s going to be tough for the rest of the season.
“We hope it’s not a big issue but there’s not much time to recover. He’s twisted his ankle and we will see how he reacts in the next few hours.”
With the 25-year-old off the pitch, Heung-min Son struck with just 12 minutes of normal time remaining to give Spurs a vital 1-0 lead over City heading into the return leg next week at the Etihad.
But the succession of ankle injuries Kane has picked up throughout his career will be a real concern to Pochettino, who has been forced to play without his talisman already this season.
Below, talkSPORT.com examines Kane’s injury history to determine how Spurs cope without their star striker and if there is a serious issue to address.
September – November 2016
Kane first sustained an ankle injury in a 1-0 Premier League win over Sunderland in September 2016 – where he scored the winner. He fell awkwardly in the final few minutes and scans revealed ligament damage.
He ended up missing 10 Tottenham games in total, also missing an international break and returned for a 1-1 draw at Arsenal on November 6.
Spurs had a mixed time without him, winning the first four games of his absence, including a 2-0 success over Manchester City, but then things went south as they lost two and drew four of the next six – a run of games which saw them knocked out of the EFL Cup and suffer damaging results in their Champions League group campaign.
March – April 2017
The England striker suffered a repeat problem in the early stages of the 6-0 FA Cup win at Millwall in March 2017.
He tangled with Jake Cooper after getting a shot away and was unable to continue. Fears were that he would be out for a similar period to his absence earlier in the same season but he only missed three Spurs games, all of which resulted in wins.
He returned as a substitute against Watford in early April.
March – April 2018
Almost one year on from his last problem, Kane went down again and it was a worrying time for both Tottenham and England fans ahead of the World Cup.
It looked serious as the striker had to limp off against Bournemouth after being caught trying to turn the ball into the net. However, it was a quickfire recovery from Kane, who only missed one Tottenham game, along with two England matches as he returned for the away win at Chelsea.
Spurs won their only game without him, an FA Cup success at Swansea.
Another ankle problem for the England captain. He went down at the end of the 1-0 defeat by Manchester United and did not return to action until they played at Burnley nearly six weeks later – returning with a goal.
Spurs won five of their seven matches without their talisman, including a 3-0 Champions League win over Borussia Dortmund.