The centre-back was replaced by Stephan Lichtsteiner following a collision with Marcus Rashford during the Premier League clash with Manchester United
Rob Holding left Arsenal’s clash with Manchester United on a stretcher after appearing to injure his left knee.
The 23-year-old came off worse following a collision with Marcus Rashford in the 36th minute of the Premier League match.
Holding clutched his left leg as he fell and received treatment on the pitch.
However, he could not continue and was eventually replaced by Stephan Lichtsteiner.
Speaking on BBC Radio 5 live, ex-Leicester City star Robbie Savage predicted that Holding suffered ligament damage.
He said: “It looks like knee ligament damage and the medical team were possibly doing tests on the side of the field.
“He stood up and was in a lot of pain. It is a shame because he has been playing well.”