The International break is over and Premier League teams must now pick up the pieces after 18 players suffered injuries.
Some will be tiny, some will be niggles, but others are likely to be bigger problems as the players’ club scan and assess the issues.
Injuries can happen at any time but there appears to have been a lot more than normal this time around with players struggling physically already.
But which superstars suffered injury issues while on duty for their respective nations? Find out below.
Wilfred Zaha (Crystal Palace)
The skilful forward withdrew from the Ivory Coast squad after picking up a ‘slight injury’ in training ahead of their match with Central African Republic. The Eagles are currently assessing him in south London.
Danilo (Manchester City)
The Brazil full-back, 27, left the pitch in tears on Tuesday night in Saudi Arabia after rolling his ankle against Argentina. It’s the latest injury for the ex-Real Madrid star who hasn’t had much luck in that department, having been ruled out the World Cup and City’s pre-season with a similar injury.
Ciaran Clark (Newcastle United)
The Irish defender suffered a thigh injury on international duty and is now a doubt for the Magpies’ clash with Brighton on Saturday.
Naby Keita (Liverpool)
The Guinean midfielder was injured in their 1-1 draw with Rwanda in an Africa Cup of Nations qualifier, and carried off the pitch by a team-mate. He’s now set for a scan on a reported hamstring problem to figure out the extent of the issue.
Stephen Ward (Burnley)
The versatile Clarets star had to pull out of the Republic of Ireland squad to face Denmark and Wales and after seeing a specialist he’s now had surgery to clean up the troublesome issue in his knee.
Philip Billing (Huddersfield)
The Denmark Under-21 star was forced to return to Huddersfield after picking up a knock on ahead of their UEFA European Under-21 Championship qualifier against Faroe Islands, although the location and extent of the injury is unconfirmed.
Sokratis Papastathopoulos (Arsenal)
Greek summer signing Sokratis may miss their upcoming match with Leicester City having been substituted at half-time of his nation’s defeat to Finland due to an ankle problem.
Sadio Mane (Liverpool)
The Anfield club are set to assess the Senegalese star’s broken thumb on his return to Merseyside. It appears he is set to miss just one game, against Huddersfield this weekend.
Arthur Masuaku (West Ham)
Marauding left-back Masuaku withdrew from the Democratic Republic of Congo squad having picked up an injury in the 2-1 loss to Zimbabwe. It’s reported he has an ankle issue but could still play against Tottenham on Saturday.
Gaetan Bong (Brighton)
Ruled out of Cameroon’s Africa Cup of Nations qualifier with Malawi, not much is known about the injured Bong has suffered.
Shane Long (Southampton)
Striker Long ‘took a few knocks and bruises’ against Denmark, according to Republic of Ireland boss Martin O’Neill. He will be assessed by the Saints.
Stuart Armstrong (Southampton)
Ex-Celtic star Armstrong limped off during Scotland’s 3-1 defeat to Portugal after 77 minutes, with what looked like a calf problem.
Victor Wanyama (Tottenham)
Kenya midfielder suffered a problem in his nation’s 3-0 win over Ethiopia, in which he scored. It is, though, believed the injury is ‘not serious’ and he should be available to face West Ham.
Virgil van Dijk (Liverpool)
Netherlands head coach Ronald Koeman has revealed the Dutchman has been playing with two broken ribs for several weeks. He is fit to play against Huddersfield but is carrying the problem.
Idrissa Gueye (Everton)
Senegal star Gueye scored against Sudan but also went off with what appeared to be an ankle injury that will have Everton sweating.
Robert Snodgrass (West Ham)
He missed Scotland’s defeat to Israel and then withdrew from their squad due to an ankle problem but should be fit to face Tottenham.
Mohamed Salah (Liverpool)
The Egyptian limped out of his nation’s 4-1 win over eSwatini last Friday with a muscle strain. Egypt’s team doctor reportedly believed the issue wasn’t serious but he will be a doubt to face Huddersfield.
Ethan Ampadu (Chelsea)
Young Blues star Ampadu picked up a knee injury against Spain and missed Wales’ next game against Republic of Ireland.